Authorized: U.S. stocking partner for Joint Glide|2 capsules each morning · 30 days a bottle|Every amount printed. 10 of 10, no proprietary blend|+1 (727) 351-3065|Lot JOI-26/TH-3366
ThejointglideU.S. stocking partner

Joint Glide Side Effects: Cautions and Interactions to Know

One ingredient accounts for most of this page, and the label carries no caution panel to mention it.

Quick answer

The main Joint Glide caution is its white willow bark, which contains salicin.

Memorial Sloan Kettering advises against it with warfarin, other blood thinners or NSAIDs, in people with aspirin sensitivity, asthma or stomach ulcers, and for children. Glucosamine is often made from shellfish.

Ask a pharmacist first if any of these apply, and see who it suits.

The sentence to read before anything else

If you take warfarin or another blood thinner, daily aspirin, or NSAIDs regularly, show a pharmacist the Supplement Facts panel before you buy this product.

That is the firmest sentence on this website and it is the one we would keep if we had to delete every other line. It is not a prediction that something bad will happen; it is a statement that this specific question belongs to somebody who knows what else you take.

There is one practical advantage here that most products in this aisle do not offer. Because this label prints an amount for every ingredient and hides nothing in a proprietary blend, a pharmacist can actually assess it. Photograph the panel and hand over the photograph.

What the label does not do is say any of this itself. No caution panel, no age restriction and no pregnancy statement appears on the label images we were given, which on a product containing a salicylate source is the one serious gap on an otherwise careful piece of work.

Our position, labelled as ours

Treat this as an adults-only supplement, not for use in pregnancy or while nursing, not for children, and worth a pharmacist conversation if you take anything that affects bleeding or the stomach. The manufacturer has not said that; we are saying it.

White willow bark, salicin, and what follows from it

White willow bark extract is 150 mg of the two-capsule serving, fifth by weight on the panel.

Memorial Sloan Kettering states the connection plainly: “Aspirin is derived from salicin, an active compound in willow bark”, and notes that “aspirin-like side effects may occur with willow bark”.

Blood thinners. “Do not take if you are taking warfarin or other blood thinners: Willow bark may increase the risk of bleeding.” The same page notes that salicin “may affect blood clotting”, and that the clinical significance in patients with impaired platelet functioning is yet to be determined.

NSAIDs. Avoid combining willow bark with NSAIDs because of the increased risk of stomach damage. Anyone already taking ibuprofen or naproxen for a joint problem is exactly the person most likely to reach for this product.

Aspirin sensitivity, asthma, ulcers. The same source lists aspirin sensitivity, asthma, breathing problems, stomach issues and ulcers among the reasons to avoid it.

Children. “Children should not be given willow bark because of the potential for developing Reye syndrome, a serious condition associated with the use of aspirin.”

On effectiveness, the same source is measured: clinical trials suggest willow bark extract is effective for back pain, while results are mixed for osteoarthritis.

And the specification gap: the label prints 150 mg of extract and no salicin percentage. Every caution above is dose-related in principle, and the dose of the relevant compound cannot be established from the label.

The shellfish question

Glucosamine is commonly manufactured from the shells of crustaceans. Not always — fermented and corn-derived vegetarian glucosamine exists — but commonly enough that it is a standard question for anyone with a shellfish allergy.

This label carries a Soy Free mark printed on the panel, so allergens were clearly thought about. There is nothing about shellfish.

That makes the omission more surprising rather than less. A manufacturer who printed one allergen statement had the opportunity to print the one that actually applies to an ingredient in their own formula.

If you have a shellfish allergy, this is an answerable question and the order desk on +1 (727) 351-3065 should be able to answer it. Ask before you buy rather than after, and do not infer anything from the vegetarian mark on the listing: that mark is about the capsule shell.

Three more things worth knowing

1

The minerals are unremarkable

Copper at 2 mg is a fifth of the 10 mg tolerable upper intake level. Zinc at 10 mg is a quarter of its 40 mg limit. Magnesium at 100 mg is well inside ordinary supplemental practice. Those sentences are only possible because the amounts are printed.

2

Magnesium and the bathroom

Magnesium in supplemental amounts is a well-known cause of loose stools, and 100 mg is a modest amount unlikely to cause it on its own. Worth knowing if you already take magnesium separately.

3

Devil's claw and the stomach

Devil's claw is traditionally cautioned against in people with gastric or duodenal ulcers. Combined with the willow bark caution about stomach damage, anyone with an ulcer history has two reasons to ask first rather than one.

The caution panel that is not there

Most supplements in this category print a short block on the label: do not exceed the recommended dose; not for use by those under 18 or by pregnant or nursing mothers; consult a physician before use if you are taking medication or have a medical condition; keep out of reach of children.

None of that appears on the label images we were given for this product. The brief says adults 18 and over, following the label, but the label as supplied to us prints no age restriction at all.

We are not going to write that block ourselves and present it as the manufacturer's, because it is not theirs. What we can say is that every line of it would apply here, and that on a product containing a salicylate source the children's line is not boilerplate at all.

It is the one place where this label falls behind labels that are otherwise much worse than it. A panel that discloses everything and warns about nothing is an odd combination, and we would rather say so than let the good parts carry the page.

Every source on this page

  1. U.S. Code of Federal Regulations, 21 CFR 101.36. Nutrition labeling of dietary supplements. Sets out the Supplement Facts panel a dietary supplement must bear, including the serving size, the amount per serving of each dietary ingredient and, where one exists, the percent of the Daily Value. View source
  2. Memorial Sloan Kettering Cancer Center, About Herbs: Willow bark. “Aspirin is derived from salicin, an active compound in willow bark.” “Do not take if you are taking warfarin or other blood thinners: Willow bark may increase the risk of bleeding.” “Children should not be given willow bark because of the potential for developing Reye syndrome, a serious condition associated with the use of aspirin.” View source
  3. National Center for Complementary and Integrative Health. Glucosamine and chondroitin for osteoarthritis. “A 2018 combined analysis of 29 studies in people with knee osteoarthritis showed that global pain was significantly reduced by glucosamine or chondroitin taken separately but not by the combination of the two.” It also notes that studies of prescription glucosamine sulfate showed more favourable results than those using other formulations. View source
  4. National Institutes of Health, Office of Dietary Supplements. Copper: fact sheet for health professionals. “The DV for copper is 0.9 mg (900 mcg) for adults and children age 4 years and older.” Tolerable upper intake level for adults: 10,000 mcg. “High dietary intakes of zinc can interfere with copper absorption, and excessive use of zinc supplements can lead to copper deficiency.” View source
  5. National Institutes of Health, Office of Dietary Supplements. Zinc: fact sheet for health professionals. The Daily Value for zinc is 11 mg for adults, with a tolerable upper intake level of 40 mg. View source
  6. National Institutes of Health, Office of Dietary Supplements. Magnesium: fact sheet for health professionals. “The DV for magnesium is 420 mg for adults.” On form: magnesium “in the aspartate, citrate, lactate, and chloride forms is absorbed more completely and is more bioavailable than magnesium oxide and magnesium sulfate”. View source
  7. National Institutes of Health, Office of Dietary Supplements. Vitamin B6: fact sheet for health professionals. The Daily Value for vitamin B6 is 1.7 mg for adults. View source
  8. Rose BJ, Kooyman DL. A Tale of Two Joints: The Role of Matrix Metalloproteases in Cartilage Biology. Disease Markers, 2016; article 4895050. This paper appears as a screenshot inside the brand's own marketing material; we looked it up and it is a real review of cartilage enzyme biology. It is not a study of this product. View source
  9. Cowell W, Ireland T, Vorhees D, Heiger-Bernays W. Ground Turmeric as a Source of Lead Exposure in the United States. Public Health Reports, 2017 May/Jun;132(3):289-293. Also a real paper appearing as a screenshot in the brand's marketing. It is about lead contamination in ground turmeric, and this product contains no turmeric. View source
  10. U.S. Food and Drug Administration. Questions and answers on dietary supplements. “FDA does not have the authority to approve dietary supplements before they are marketed.” View source

Every source above was opened and read. Studies that found nothing are included on purpose.

This is not medical advice

It is a compilation of what named public sources say about ingredients printed on this label, published so you can take it to somebody qualified. If you take a blood thinner, daily aspirin or regular NSAIDs, that person is a pharmacist, and asking before the first capsule is better than asking after the first month.

Joint Glide Side Effects, Interactions And Cautions: common questions

What should I know about the white willow bark?

This is the most important safety line on the site. Aspirin was originally derived from salicin, the active compound in willow bark. Memorial Sloan Kettering warns: do not take it if you are taking warfarin or other blood thinners, because willow bark may increase the risk of bleeding; avoid combining it with NSAIDs; avoid it in aspirin sensitivity, asthma, breathing problems or stomach ulcers; and children should not be given willow bark because of the potential for Reye syndrome. No salicin percentage is stated on this label.

I have a shellfish allergy. Can I take it?

Ask the order desk before you buy. Glucosamine is commonly manufactured from shellfish, and this label carries a Soy Free mark but says nothing about shellfish either way. It is the one allergen question the label does not answer and it is a specific, answerable question.

I take ibuprofen or naproxen regularly. Does that matter?

It may. Sloan Kettering advises avoiding willow bark in combination with NSAIDs because of the increased risk of stomach damage, and separately advises against it in people with stomach issues or ulcers. That is a conversation for a pharmacist rather than a website.

I take prescription medicine. Can I take this?

Show a pharmacist the panel first. The specific concern is the white willow bark, because salicin has aspirin-like effects and Sloan Kettering warns about bleeding risk with warfarin and other blood thinners. Because this label prints every amount, a pharmacist can actually assess it, which is not true of most supplements in this aisle.

Is it safe?

For a healthy adult not taking blood thinners, NSAIDs or aspirin, and with no aspirin sensitivity or shellfish allergy, nothing on this panel stands out as alarming at the printed amounts — and unusually, the amounts are printed, so that sentence means something. The conditions in it are doing real work: willow bark carries specific cautions and glucosamine carries a specific allergen question.

Can I take it while pregnant or nursing?

The brief says adults 18 and over. We would add a firmer line than the label does: willow bark is a salicylate source and salicylates are generally avoided in pregnancy without medical advice. Ask before, not after.

Is it for anyone under 18?

No, and here the reason is specific rather than general. Sloan Kettering states that children should not be given willow bark because of the potential for developing Reye syndrome, a serious condition associated with the use of aspirin.

222% of the Daily Value for copper — is that safe?

2 mg is a fifth of the 10 mg tolerable upper intake level the NIH gives for adults, so the percentage looks large mainly because the Daily Value is small at 0.9 mg. It is also there for a reason: the NIH notes that excessive zinc supplementation can lead to copper deficiency, and this formula carries 10 mg of zinc. Pairing them is the correct decision.

Is the capsule vegetarian?

The shell is cellulose — a plant material — and the only other ingredient is olive oil, so the capsule itself is. The separate question is the glucosamine, which is commonly manufactured from shellfish and which the label does not address. If that matters to you, ask the desk.

Ready to try Joint Glide?

One bottle is 60 capsules. How many days that is depends on a serving size nobody published, so we cannot tell you. The 60-day guarantee runs from purchase either way, and the price is shown at checkout.

Order NowRead the label firstNo price was published to us. We print no figure we have not seen ourselves. · 60-day guarantee from purchase · Not for under 18, pregnancy or nursing
Joint Glide · 60 capsules10 of 10 amounts printed · 30 days a bottle · price shown at checkout
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